Fig. 8

Results of 6 selected genes which are mitochondrial morphology controllers. Although the fold change was not significant, we choose the genes which the FDR p-value <0.05 to conduct qPCR analysis, indicating a potential involvement in mitochondrial morphology control. Confirmation of the RNA levels and protein expressions of Opa1, Mfn2, and Fis1, with FDR p-values <0.05. The results indicate that PT320 might have a major influence on Opa1 and Fis1, but not on Mfn2. A Summary of NGS results of selected genes. B The qPCR results of the Opa1, Mfn2, and Fis1 genes. C Protein expression of Opa1, Mfn2, and Fis1. (N = 3-6)